Why Patients Need You

Whether you are involved in the design and development of manufacturing processes for products or supporting maintenance and reliability, engineering is vital to making sure customers and patients have the medicines they need, when they need them. Working with our innovative engineering team, you'll help bring medicines to the world even faster by imagining what’s possible and taking action.

What You Will Achieve

Working with Pfizer’s dynamic engineering team, you will play a critical part in managing the maintenance and reliability engineering activities involving the redesign, maintenance, and repair of utilities systems, buildings, and production/non-production equipment.

You are recognized as a subject matter expert with specialized knowledge and skills in procedures, techniques, tools, materials and equipment. You will be entrusted with adapting standard methods and procedures by applying your knowledge, prior work experience and requirements. Your business awareness of cross-organizational impact on project delivery will elevate the quality of project deliverables. You will arrive at decisions on which methods and procedures are the best fit for different work situations.

You will train others and reinforce behaviors that will help us achieve our goal of providing the best healthcare to our patients.

How You Will Achieve It

• Working within the Reliability Maintenance environment, performs preventive maintenance, modifies, installs, and maintains company machinery systems and provides training in the implementation and operation of those systems in compliance with company standards and procedures and government regulations (SOPs, GMPs, GLPs, PSM, etc). Can serve as a maintenance advisor in areas of engineering (process design, material selection, documentation, calibration, testing and problem solving methodology, project scope and follow up). Responsible for priority assessment and decision making as it relates to troubleshooting, diagnostics, assembly, repair, and a proactive maintenance of systems and equipment in a cost effective manner.

Qualifications

Must-Have

• High School Diploma or GED
• Electrical license
• 4+ years of experience
• Certification in assigned area, if applicable
• Demonstrated aptitude in basic mechanical, electrical and instrumentation skills and problem-solving techniques.
• Knowledge of industry practices and standards
• Knowledge of basic mathematics
• Knowledge of the general trades, that is, construction, electrical, machine shop
• Well-developed time management and problem-solving skills
• Excellent communication skills and strong work ethic

Nice-to-Have

• Working knowledge of Pharma Utility systems and operations

PHYSICAL/MENTAL REQUIREMENTS

Potential for routine exposure to hazardous materials, heights, temperature extremes, equipment in motion, dusty and dirty conditions, stooping, bending and heavy lifting. May work variable shifts and 24 hour on-call as required.

The proper use of the correct Personal Protective Equipment for each task as well as compliance with all applicable safety Standard Procedures is a must.

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

May work variable shifts and 24 hour on-call as required. Participates in Multicraft work activities as required.

Work Location Assignment: On Premise

Relocation assistance may be available based on business needs and/or eligibility.

ROLE SUMMARY

Executive Administrative Lead to Pfizer’s Chief Medical Officer (CMO), Head of Worldwide Medical & Safety, provides administrative and office services of a highly complex and critical nature. The Executive Administrative Lead is expected to be able to work autonomously with exceptional professionalism and attention to detail with work that involves time-sensitive and urgent issues, tight time frames, and in demanding situations. This role will also be expected to think creatively about how we can continue to run the office more efficiently. This role will be a key member of the Office of Pfizer’s CMO.

This position will provide a full range of executive level administrative support to the CMO. The ideal individual will have the ability to exercise good judgment in a diversity of situations, with strong communication, collaboration, administrative, and organizational skills, and the ability to maintain a realistic balance among multiple priorities.

As part of the administrative support team, you are recognized as an advisor to other colleagues in your group due to your comprehensive knowledge and skills in your area and understanding of the larger organization. You are innovative in identifying solutions to problems by taking a broader perspective that benefits the organization. You encourage collaboration and communication within the team and across groups to influence desired outcomes. You train others and provide guidance to the team that helps us achieve our goal of creating breakthroughs that change patients’ lives.

ROLE RESPONSIBILITIES

• Manage sensitive matters with a high level of confidentiality and discretion.
• Monitor CMO’s mailbox including sending and responding to emails on the leader’s behalf, bringing critical/time sensitive matters to immediate attention.
• Manage CMO calendar which includes meeting scheduling, maintaining full year schedule of speaking engagements, conference room reservations, teams meetings, audio/video set-up and associated meeting logistics (i.e., catering, collecting conference agendas and forms, follow-up with conference organizers, etc.)
• Manage complex calendar and anticipate conflicts and use diplomacy to resolve problems in advance.
• Proactively and independently organize and expedite workflow and initiate follow-up when necessary to ensure schedules and deadlines are met.
• Work closely with Chief of Staff on operational planning, updating LT org charts, LT meetings, LT offsites, and other CMO commitments.
• Responsible for all logistics of meetings including conference room reservations, teleconference, videoconference, food ordering and associated meeting logistics.
• Collaborate with Chief of Staff, PX Lead and Communications partners on planning for Town Halls, Extended Leadership Team Meetings, Site Visits and other communication and engagement events.
• Proactively prepare meeting materials in advance
• Prepares registration for conferences and speaking engagements. Provides all information required by conference organizers (bio, photo, speaker form, etc.). 
• Organizes all domestic and international travel for business, including aviation arrangements, hotel accommodations, ground transport, travel documents, visas/passports, and presentation materials for meetings. Prepares detailed itineraries.
• Support logistics and planning of offsites. Research options for meeting venues and cost.
• Prepare expense reports, track reimbursements, and ensure correct AMEX credits/debits; manage purchase orders through Ariba system and tracking invoices.
• Maintain impeccable records and files of CMO documents for auditing purposes.
• Handle the coordination of PE Requests, ensure proper invoice routing and tracking and interfaces with vendors.
• Coordinate and provide key information to other enterprise partners as appropriate.
• Order office supplies and IT equipment as requested.
• Work closely with other Administrative Partners within WMS and across the Pfizer R&D Leadership Team
• Use appropriate discretion in the management of information and stakeholders.

BASIC QUALIFICATIONS

• 5+ years of demonstrated executive administrative assistant experience with 2+ years providing 1:1 executive level support required.
• Ability to carry out all office and administrative functions proficiently, with high quality on a timely basis required.
• Must have the ability and professional demeanor to interface with senior management, international colleagues and important external stakeholders and must be able to exhibit good judgment in handling confidential information.
• Demonstrated resourcefulness with proven ability to anticipate needs, prioritize responsibilities, manage multiple priorities with tight timelines, and take initiative.
• Demonstrated ability to be change agile.
• Demonstrates Pfizer Values.
• Flexible work hours required (early mornings, evenings and/or weekends, as needed).

Required Skills

• Possess excellent communication skills with an ability to respond with professionalism in verbal and written communications with all levels of the organization, including C-Suite.
• Proficiency in MS Word, Excel, PowerPoint, Teams and Outlook are essential.

PREFERRED QUALIFICATIONS

• Associates degree or Bachelor’s degree preferred.
• 10 years administrative assistant experience preferred.
• Bachelor’s degree strongly preferred.
• Strong knowledge of Pfizer headquarters environment.
• Knowledge of Pfizer organizational processes.
• Proficiency in Pfizer systems (e.g., Ariba, SharePoint, Concur, and Workday).
• Knowledge of Pfizer corporate compliance policies, T&E policies, etc.

Relocation assistance may be available based on business needs and/or eligibility.

Why Patients Need You

Whether you are involved in the design and development of manufacturing processes for products or supporting maintenance and reliability, engineering is vital to making sure customers and patients have the medicines they need, when they need them. Working with our innovative engineering team, you'll help bring medicines to the world even faster by imagining what’s possible and taking action.

What You Will Achieve

Working with Pfizer’s dynamic engineering team, you will play a critical part in managing the maintenance and reliability engineering activities involving the redesign, maintenance, and repair of utilities systems, buildings, and production/non-production equipment.

You are recognized as a subject matter expert with specialized knowledge and skills in procedures, techniques, tools, materials and equipment. You will be entrusted with adapting standard methods and procedures by applying your knowledge, prior work experience and requirements. Your business awareness of cross-organizational impact on project delivery will elevate the quality of project deliverables. You will arrive at decisions on which methods and procedures are the best fit for different work situations.

You will train others and reinforce behaviors that will help us achieve our goal of providing the best healthcare to our patients.

How You Will Achieve It

• Perform maintenance, changeovers, adjustments and repair of production and process equipment, the general facility, and utility equipment.
• Participate in multicraft work activities as required.
• Responsible for priority assessment and decision making as it relates to troubleshooting, diagnostics, and a proactive maintenance of systems and mechanical equipment in a cost-effective manner.
• Participate in safety training programs and utilize tools, equipment etc. in a safe manner as per plant safety procedures.
• Read and follow equipment schematics, logic diagrams and engineering drawings.
• Use electrical testing equipment, including multimeters, clamp-on current meters, meggers etc. in a safe manner.
• Make recommendations regarding improved machine performance.
• Follow all SOP and (Current) Good Manufacturing Practices (part of GxP) requirements.
• Provide customer training in the implementation of those systems in compliance with company standards and procedures, and government regulations (SOPs, GMPs, GLPs, PSM, etc.).
• Responsible for providing input to performance assessment on team members.
• Manage own time, professional development and accountable for own results.
• Prioritize own workflow and may lead and allocate work of others and assist in establishing their priorities.

Qualifications

Must-Have

• High School Diploma or GED
• 6+ years of experience
• Certification in assigned area, if applicable
• Demonstrated aptitude in basic mechanical, electrical and instrumentation skills and problem-solving techniques
• Knowledge of industry practices and standards
• Knowledge of basic mathematics
• Knowledge of the general trades, that is, construction, electrical, machine shop
• Well-developed time management and problem-solving skills
• Excellent communication skills and strong work ethic

Nice-to-Have

• Working knowledge of Pharma Utility systems and operations

  
Work Location Assignment: On Premise

Relocation assistance may be available based on business needs and/or eligibility.

Why Patients Need You  

 Pfizer’s purpose is to deliver breakthroughs that change patients’ lives. Research and Development is at the heart of fulfilling Pfizer’s purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.  

What You Will Achieve  

 Pfizer is making significant investment in the creation of novel, first-in-class therapeutics for the Pfizer pipeline.  We are seeking an exceptional in vitro pharmacologist and laboratory automation head to join the Primary Pharmacology Group (PPG) at our Groton, CT campus and drive expansion and strategic execution of Pfizer’s internal HTS capabilities for small molecule lead identification across the diverse Discovery & Early Development portfolio. Your work will play a key role in addressing the critical task of rejuvenating the Pfizer research pipeline with innovative, differentiated First in Class programs in the years to come. 
 
As an Associate Research Fellow, you will be at the center of our operations and you’ll find that everything we do, every day, is in line with an unwavering commitment to quality. You will drive the rebuilding of Pfizer’s internal HTS capability within the Discovery Sciences department and its implementation. You will oversee the deployment of capital to assemble a state of the art screening infrastructure and build a dedicated team of scientists with relevant skills to ramp up internal HTS capabilities while leveraging external CROs as required. Thus, this role requires technical excellence in the execution of disease relevant pharmacology approaches to support HTS, laboratory automation, and data strategies. Additional desired areas of expertise include high content imaging or analytical expertise in mass spectrometry.  

The successful candidate will combine strong technical/scientific rigor, strategic planning, leadership and problem-solving skills with a demonstrated ability to build, energize and lead high-performing teams to drive impact across multiple drug discovery programs. This individual should therefore possess exceptional collaborative and written/verbal communication skills, a good sense of humor and be adept at building partnerships. The role will have high visibility across the research organization so an executive presence and ability to gain the respect of stakeholders is key.Through your expertise and extensive knowledge, you will be able to foster a culture that promotes innovation and thrives on doing better for patients and healthcare. 

How You Will Achieve It  

• We are seeking an experienced pharmacologist and automation specialist to build and lead the HTS laboratory to support small molecule drug discovery. The laboratory head will also be responsible for automation and data management and lifecycle strategies within PPG.

• As the HTS portfolio lead, you will be responsible for management, communication, and execution of the HTS portfolio as well as and the strategic vision for HTS moving forward. This will include extracting value from HTS data beyond immediate project needs.   
• This laboratory leader will maintain a ‘cutting edge’ awareness of technical developments and scientific advancements in the field and apply these innovatively to advance internal capabilities. The role includes opportunities to publish when appropriate.
• This HTS lead will lead interdisciplinary team(s) of biologists, medicinal chemists, and protein biochemists to effectively prosecute the HTS portfolio and actively interact with other groups in Discovery Sciences.
• As a laboratory supervisor, a commitment to coaching and guiding professional development is required.

Qualifications  

Must-Have  

• PhD in Molecular Biology, Biochemistry, Cell Biology, and/or Pharmacology with 10+ years post-degree experience, including industry experience
• Proven ability to build, lead, energize and develop a high-performing team of scientists.
• Demonstrated examples of strong scientific leadership, independent thought and creativity, and ability to integrally contribute to program strategies and execute plans.
• Experience successfully interacting with and meeting the needs of stakeholder groups is essential as well as having a customer focus.
• Demonstrated experience with multiple plate-based pharmacology formats (e.g. FRET, FACS, FP, ELISA, high content imaging, FLIPR, radioligand binding, nanoBRET etc.), mass spectrometry (HTMS, LC-MS, AEMS) including assay development and troubleshooting
• Demonstrated proficiency in laboratory automation and data analysis with excellent computer, verbal and written communication skills
• A strong publication and presentation record showcasing scientific leadership in pharmacology and drug discovery.

Nice-to-Have  

• Previous experience in multiple target classes (e.g. GPCRs, transporters, kinases, ion channels, DUBs, RNA) in a drug discovery setting
• Experience with phenotypic screening and hit deconvolution
• Demonstrated ability to forge strong collaborative and inclusive relationships inside and outside organizational walls and across multiple cultures: academic, industrial, and CROs

 
Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
 

PHYSICAL/MENTAL REQUIREMENTS

Sitting, standing, lifting, bending, and walking.  Ability to perform practical laboratory bench work and work on a computer (while standing or sitting).  Ability to perform mathematical calculations and interpret data.

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

• Travel to attend appropriate meetings and conferences.
• Compliance with laboratory safety practices.

Relocation support available

Work Location Assignment: On Premise

Relocation assistance may be available based on business needs and/or eligibility.

ROLE SUMMARY

• Support clinical trials and the development strategy for early development assets and lead development programs across multiple functions within Pfizer Oncology, as well as represent the program with the external clinical community.
• Develop clinical development plan from first in human clinical trial to proof-of-concept, including assessment of appropriate combinations, as well as evaluation of potential predictive and pharmacodynamics biomarker plans.
• To ensure the clinical components of the clinical plans and clinical expertise are provided to project teams, including medical monitoring of clinical trials. 
• To support projects from Research to Proof of Concept at which point molecule may be handed to the late-stage Oncology Clinical Development team for post-POC (typically phase 3) development

ROLE RESPONSIBILITIES

• Lead, develop and execute strategic development for early development assets.
• Oversee early development assets’ development broadly within a specific indication or group of indications. Typically, work on at least two clinical programs and support the development and provide consultation regarding multiple research projects.
• Work across the organization and on multifunctional teams responsible for the development of early development assets (including Product Team).
• Oversee the development and management of clinical protocols and amendments, investigator brochures, clinical study reports, statistical analysis plan, and regulatory documents.
• Provide leadership to early stage clinical scientists on the clinical study team for Early Development Assets, working in a matrix team environment with other clinicians, statisticians, clinical pharmacologists, translational biologists and regulatory specialists. Meet regularly with the Pfizer Oncology group leaders/surrogates across functions to increase mutual awareness and influence of emerging program targets, priorities and status.
• Implementation of PK-guided dose escalation, early combination strategies and emerging innovations on all Pfizer Oncology first-in-human clinical trials with input from Oncology Research Unit, Oncology Regulatory Strategy, Clinical Pharmacology and Precision Medicine, Oncology Clinical Development and Operations, Pharm Sci and Product Teams.
• Oversee the evaluation of safety, pharmacology, and efficacy data from ongoing and completed studies for early development assets.
• Oversee manuscripts, abstracts and presentations for scientific meetings and advisory boards.
• Conduct literature reviews and prepare summaries to support clinical development programs.
• Medical resource for design and interpretation of clinical and preclinical programs to support existing and new development candidates.
• Coordinate regular (at least quarterly and as needed) interactions with preferred clinical trials network and KOL advisory board to objectively consider and implement feedback.
• Drive innovations in early clinical development, and the application of translational oncology and precision medicine approaches.
• Collaborates with cross-functional leaders and teams to translate early preclinical discovery research into therapeutic candidates.
• Coordinates with business development to establish strategic external collaborations and foster new research projects and programs.

BASIC QUALIFICATIONS

• MD or MD-PhD with 5-10 years of industry experience in oncology drug development is preferred, track record in early phase drug development.
• Clinical oncology experience: Board certification in oncology preferred.
• Significant industry leadership experience in clinical, translational or basic research in biomedical sciences or one of the disciplines related to drug development.
• Understanding of related disciplines (e.g., biostatistics, regulatory, pre-clinical pharmacology, pharmaceutical sciences). 
• Demonstrated scientific productivity (publications, abstracts, etc.).
• Proven scientific writing skills and good communication skills.
• Proven leadership skills with ability to defend the clinical plan at governance meetings is essential.
• Capacity to adapt to a fast-paced and changing environment.
• Demonstrated history of effective leadership; including cross functional and matrixed teams, managing direct reports, and experience in seeking and maintaining alignment with cross-functional leaders.
• Demonstrates a passion for helping patients with cancer and for the science of oncology.

PREFERRED QUALIFICATIONS

• Has a strong leadership presence and the ability to work effectively with other clinical and scientific leaders.
• Has a collaborative style with internal company leadership, external development partners and investigators/medical professionals.
• Is a team player, works well in a team environment both as a leader and a key contributor.
• Has a global perspective and mindset, with the ability to work effectively with colleagues from myriad cultures, backgrounds, and geographies

Relocation assistance may be available based on business needs and/or eligibility.

Why Patients Need You

Pfizer’s purpose is to deliver breakthroughs that change patients’ lives. Research and Development is at the heart of fulfilling Pfizer’s purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.

Position Summary

A Senior Scientist in the Compound Management (CM) Data Support team plays an important role in the stewardship of the Pfizer compound collection specializing in solutioning, data flows, and material workflows & logistics. You will collaborate with the Primary Pharmacology Group (PPG), hit follow-up, lead optimization, External Research Solutions, and Medicinal chemistry stakeholders, to ensure timely, high-quality access to the Pfizer compound collection.  Partnerships with Digital, Contract Research Organizations, and external software & hardware vendors are also a key aspect of the role.  As a senior member of the CM Data Support team, you will also have significant input in defining plans and strategy for the team.

Key Responsibilities

• Collaborate with stakeholders, both internal & external, to analyze business requirements and design & implement lab-specific information & data-driven solutions.

• Provide daily technical subject-matter-expert expertise, troubleshooting assistance and guidance on the applications and tools, both at the enterprise level & lab specific level, that support CM workflows to other CM colleagues and internal stakeholders.

• Collaborate and partner with Pfizer Digital to develop lab-specific solutions that address CM workflow, data mining, analysis, storage, and curation requirements, and adhere to Digital enterprise level requirements, such as security, change & configuration management.

• Participate in CM project teams as a key contributor by providing insight & expertise on data handling, applications, laboratory automation & material logistics to solve issues of significant complexity and improve the efficiency of operations in Compound Management.

• Produce high-quality and detailed documentation for implemented solutions, including workflow & data diagrams, description of requirements, use cases, design, tests, users guides & standard operating procedures.

• Participate in the evaluation and testing of internally and externally developed tools and applications, providing expertise in the planning, execution, recording and reporting of results.

• Contribute to the strategic direction, daily decision-making, and operation of Compound Management, focusing on compound stewardship, efficiency, quality assurance and continuous improvement by effectively collaborating with other Compound Management teams, such as the Liquid Store, Sample Logistics, and Automation.

• Identify and champion new ideas and technological strategies that will enable innovation, continuous improvement and capability enhancements in workflows and operations within Compound Management.

• Present technological advancements & solutions internally to Compound Management stakeholders and externally to industry peers.

• Act as a technical and scientific resource within Compound Management’s data support team.

• Mentor junior team members by modeling courage & excellence in your work and contributing to an environment of equity and joy that promotes active engagement & learning.

Minimum Qualifications

• Bachelor of Science degree in Computer Science, Data Science, Information Science, Engineering, or a related field with 9+ years of relevant experience in developing solutions.

• Expertise in databases (Oracle/PostgreSQL), query languages (SQL/PLSQL), and database navigation/management tools (Toad/DBeaver).

• Experience leveraging many of the following tools & technologies:  Pipeline Pilot, SharePoint Pages/Web Parts/Power Apps, Excel Macros/Visual Basic & Diagramming Tools (Visio/Draw.io).

• Demonstrated ability to develop innovative and creative solutions applying agile & lean principles to solve complex issues to streamline workflows and minimize risks for errors.

• Comprehensive working knowledge of Microsoft applications, including Outlook, Excel, Word, PowerPoint & Teams.

• Demonstrated experience collaborating with stakeholders and external hardware & software vendors.

Preferred Qualifications

• Master’s degree in Computer Science, Data Science, Information Science, Engineering, or a related field with 7+ years of relevant experience in developing laboratory solutions in the pharmaceutical industry.

• Expertise leveraging many of the following tools, languages, & technologies: LIMS Systems/Software, Java/C#, Scripting (JavaScript/Python/Perl), HTML/XLM/JSON, APIs (REST/Soap/Microservices), Jira, Confluence, Eclipse, GitHub/SVN.

• Prior experience in pharmaceutical laboratory automation, specifically, in the operation of liquid handling systems, storage systems and other automated tube & plate handling instrumentation.

• Experience working in areas of compound management or research materials logistics.

• Basic understanding of primary pharmacology assay development and compound screening is a plus.

PHYSICAL/MENTAL REQUIREMENTS

Position will require working in the lab, operating automated equipment, lifting, sitting, standing, walking, bending and the ability to perform mathematical calculations and solve complex technical problems.

Work Location Assignment: On Premise

Relocation assistance may be available based on business needs and/or eligibility.