Research Funding and Support Officer
Full time, Permanent
Grade 7 (£37,999 - £45,163 increasing to £38,249 - £45,413 from March 2025)

Abertay is a modern university with a global outlook, rooted in its local and national communities. We have made our mark with high quality, well-directed teaching and research, and a stimulating and enriching experience for our students.
Research, Innovation and Enterprise Support Office (RIES)

You will join a small professional team and help drive the development of a newly formed RIES Office. The new RIES Office brings together staff, support and management functions from across the University, to provide an integrated, efficient, and coherent support and management service for the funding submission and award lifecycle. The RIES Office team will provide expert advice, guidance and operational support for the entire university RKE portfolio. The team will collaborate with the academic community, various university leadership groups and support services, to deliver against university and external key performance indicators to ensure the University’s compliance with major funders and government agencies.

The new RIES Office is co-located with the Graduate School team, who provide support and professional development opportunities to our vibrant postgraduate and researcher community. The teams are overseen by the Dean of Research and the Graduate School within a dedicated facility at the heart of the University. Together the RIES and Graduate School teams are central to the continued development of our excellent research culture and environment, supporting delivery of the University’s Research and Knowledge Exchange Strategy R-LINCS (https://www.abertay.ac.uk/research-overview/research-strategy-and-structure/), and achievement of its RKE ambitions.

The University now seeks to appoint a Research Funding and Support Officer.

Reporting to the Head of the Research Innovation and Enterprise Support (RIES) office, the Research Funding and Support Officer manages and supports all the administrative processes involved in identifying, applying to, securing and setting up external research funds. Acting as the main point of contact for key sponsors, researchers wishing to submit funding proposals and collaborating Institutions wishing to establish agreements, you will be expected to develop a sound working knowledge of the sponsors who support research within the University. Establishing effective professional working relationships with staff at all levels within the University as well as all relevant funding bodies will be essential to your success.

As a key member of the RIES team you will report to and work with the Head of Research Innovation and Enterprise Support to ensure accurate grant costings are created and submitted to the required deadlines and there is a smooth transition from pre- to post- award when applications are successful.

Whilst this role is specialised, you will, over time, be expected to gain experience in a number of other related areas such as research funding, finance, human resources and project management, and as such this is an ideal role for individuals keen to develop their career within university professional support services.

You will be expected to exercise initiative and will usually work independently, consulting with the academic staff, the RIES team and Head of Research Innovation and Enterprise Support as appropriate.

If you believe you have the skills and experience for this exciting and challenging role, please submit your application through our online recruitment system, which can be found at https://www.abertay.ac.uk/discover/work-here/jobs/

Committed to Equal Opportunities
Abertay University is a Scottish Registered Charity,
No: SC016040

Grade UE07: £40,247 to £47,874 per annum
School of Chemistry / IRR
Full time: 35 hours per week
Fixed Term: for 12 months (Start date Feb 2025)

The School of Chemistry is seeking a talented scientist to work in the novel and exciting field of super-resolution microscopy to characterise synaptic proteins at the nanoscale.

A successful candidate is likely to have experience with either advanced microscopy methods. Experience with single-molecule fluorescence techniques, programming (ImageJ, python, MATLAB, etc.) would be advantageous. The candidate should have an excellent academic track record commensurate with their career stage and experience.

The Opportunity:

Working with Professors Mathew Horrocks and Seth Grant, you will build on our previously published groundwork on imaging synaptic proteins in the brain. You’ll be based in the Edinburgh Single-Molecule Biophysics Group in the newly built Chemistry Hub in the Institute for Regeneration and Repair, and also work with international collaborators. The combination of academic supervision with milestone-driven research will provide you with the guidance and knowledge you need to develop your career. This is an exciting opportunity to make a real difference to the future of medical science.

Your skills and attributes for success:

Experience with advanced microscopy methods.
Immunohistochemistry experience.
Experience with programming (ImageJ, python, MATLAB, etc.) would be advantageous

Grade UE07: £40,247 to £47,874 per annum
College of Science and Engineering / School of Biological Sciences / Institute of Molecular Plant Sciences
Full time contract: 35 hours per week
Fixed Term: for 24 months


We are looking for a Postdoctoral Research Associate in alga synthetic biology to develop systems for precise nuclear regulation of the plastome.

The Opportunity:

A Postdoctoral Research Associate position in alga synthetic/engineering biology is available in the laboratory of Dr Attila Molnar at the School of Biological Sciences, University of Edinburgh. We are seeking a highly motivated researcher to take a lead role in contributing to the development of systems for precise nuclear regulation of the plastome in the green alga Chlamydomonas reinhardtii. This is a collaborative project funded by the Biotechnology and Biological Sciences Research Council (BBSRC) involving University College London, University of Cambridge, MRC Laboratory of Molecular Biology and the University of Edinburgh.

The position is available for a fixed term of two years. For further information please contact Dr Attila Molnar (email: attila.molnar@ed.ac.uk).

Your skills and attributes for success:

PhD in an appropriate and relevant subject.
Track record of internationally competitive molecular biology research in microbiology/plants/algae.
Evidence of intellectual independence and creativity, and high level of organisation and high-quality record keeping.
Good team-working, collaborative and interpersonal skills.
Excellent communication skills, including the ability to communicate effectively both orally and in writing with colleagues and collaborators.

Grade UE07: £40,247 to £47,874 per annum
CMVM / Institute for Regeneration and Repair / Centre for Inflammation Research
Full-time: 35 hours per week
Fixed Term: 3 years

We are looking for a highly-motivated, creative and organised Postdoctoral Research Fellow to join the newly‑formed, Wellcome Trust-funded Mirchandani Lab within the Centre for Inflammation Research and Institute for Regeneration & Repair to study the impact of hypoxia on monocyte biology and ontogeny in context of critical illness.

This post is advertised as full-time (35 hours per week); however, we are open to considering part-time or flexible working patterns.

The Opportunity:

This is a 3‑year post, full‑time Postdoctoral Research position to work in the group of Dr. Ananda Mirchandani. The Postdoctoral Fellow role will offer a unique mix of utilising and developing inter‑disciplinary scientific techniques, performing cutting‑edge scientific research, and establishing managerial and leadership capabilities. This post is funded by a Wellcome Trust Career Development Award (£3.1 million, 2024‑2033).

Your skills and attributes for success:

A 1st class or 2:1 degree in Immunology or related subject
with relevant post-graduate research experience and accumulated knowledge

A PhD in Immunology or associated subject or equivalent professional qualification and/or experience in the field of Immunology
Proficient in tissue harvesting, digestion and advanced (>12 parameter) flow cytometric analysis and FACS-purification of immune cells from multiple tissues in animal (mouse) models of inflammatory disease.
Generation of bone marrow chimeric mice and adoptive transfer of immune cells.
Proficient in molecular biology techniques such as preparation of material for transcriptional profiling

Grade UE06: £33,882 to £39,105 per annum
College of Science and Engineering / School of Physics and Astronomy
Full time: 35 hours per week
Open-ended: permanent post

We are looking for a Research Support Officer to provide pre- and post- award support for research projects and grant applications in the School. You will take a leading role in monitoring expenditure against available funds, providing recommendations to Principal Investigators on how to optimise use of available funds, ensuring compliance with funder regulations.

The School of Physics and Astronomy at the University of Edinburgh is committed to encouraging equality and diversity among our workforce, and eliminating discrimination. The School strives to create a more diverse, equitable and inclusive workplace for all and we are looking to actively diversify our staff. We welcome applications from all qualified candidates and in particular encourage applications from people of colour, women, people with disabilities, LGBTQ+ people and other minority and under-represented groups. We aim to ensure that our culture and systems support flexible and family-friendly working, as evidenced by our Juno Champion and Athena SWAN Silver awards.



Your skills and attributes for success:

High levels of numeracy and accuracy;
Strong financial management skills;
Experience of research grant management;
Ability to work independently, and prioritise a busy workload;
Good time management and organisational skills;
Good communication and interpersonal skills and ability to use tact and diplomacy.

Grade UE05: £28,879 to £33,232 per annum
Business School / CAHSS
Full time: 35 hours per week
Open ended: Permanent

The Opportunity:

This role works as part of the PGR Support team in the delivery of administration for postgraduate research programmes and related activities, within the Business School’s strategic objectives of high quality research programmes and an excellent student experience.

The role supports a variety of activities across postgraduate research administration, including admissions, course administration and programme support.

Your skills and attributes for success:

Good communication and interpersonal skills, both in writing and in person
An understanding and care for excellent customer service/student experience
Able to plan own activities and tasks, with well-developed organisational, time management and prioritisation skills
Resourcefulness with a proactive approach to seeking out information to ensure effective, accurate task completion
Experience working within systems, software packages and processes

Job Title and Reporting: Research Technician (1x FTE)

Grade of Post/Salary: Grade 5 £25,138 - £28,759 Reporting Line Manager: Professor James Chalmers Duration of employment: 24 months

Location: School of Medicine, Ninewells Hospital

The Respiratory Research group at the University of Dundee specialises in studies into the immunology and microbiology of respiratory diseases such as bronchiectasis, COPD and pneumonia. You will be expected to provide high quality technical assistance to Professor Chalmers and the other members of the research team. As a research technician you will play an important role in studies with direct benefit to patients such as clinical trials and patient cohort studies working alongside other research technicians within the group and overseeing the timely completion of research projects in partnership with the principal investigator, postdoctoral researchers and other research staff.

Core laboratory tasks may include processing biological samples, culture of airway epithelial cells at air liquid interface, microscopy, ELISA, and preparation of cells and biological samples for downstream processing such as flow cytometry and proteomics. You will support the principal investigator, post- doctoral researchers and PhD students as part of a multidisciplinary team. You will work collaboratively with team members to support multiple ongoing research studies where appropriate. You will work with external collaborators and internal department such as the Clinical Research Centre and core facilities to ensure the timely completion of research studies.

We are recruiting for a Grade 5 Research Technician

An opportunity has arisen for a research technician to join us within the Jackson Lab at the University of Dundee. This group will be exploring the role of Apolipoprotein E in Alzheimers Disease with an aim to target this important protein to prevent against Alzheimers Diseases.

You will be expected to provide high quality technical assistance to Dr Rosie Jackson and the other members of the research team. Core tasks will include culture of induced pluripotent stem cells derived astrocytes, HEK 293 cells, and primary astrocytes, and multiple molecular techniques including Maxiprep, ELISA, as well as in house assays of inflammation and protein thermal melt.

You will work with the principal investigator and overseas collaborators, performing laboratory research to a high standard and organising study data. You will work collaboratively with other team members including Postdoctoral fellows and PhD students to develop and validate protocols for sample collection and support curation of samples in long-term storage whilst supporting recruitment and sample collection to newly set-up clinical studies. You will be expected to work with the principal investigator to deliver research studies to a high standard in a timely manner.

The University of Dundee enjoys an international reputation for excellence that attracts top-class students and academics from across the world - with over 140 countries represented in the University community. You will be based in the medical sciences institute building at the School of Life Science. The group is part of the School of Medicine which provides outstanding medical education and training supported by world class research facilities.

Your priorities will include:

• Provide technical research support to the ApoE research group.


• Carry out laboratory-based research to a high standard.


• Work under the supervision of the principal investigator but assume responsibility for your projects.


• Maintenance of cell culture lines


• Deriving Astrocytes from induced pluripotent stem cells.


• Using various in-house assays to test drug compounds in vitro.


• Managing laboratory reagent stocks


• Contribute to group meetings an work collaboratively within the lab.

Who we're looking for:

• Proven ability to work in a multidisciplinary science team to deliver high quality research


• Experience with IPS cells is highly desirable but not a requirement.


• Ability to collaborate with members of other research groups within the University and other academic institutions.


• Capable of interpretation of raw data, assembly into summary reports and presentation to staff.


• Ability to work to deadlines and to meet milestone targets, with detailed attention to time management and multitasking.


• Flexibility and willingness to work outwith normal hours as and when required.

This role does not meet the minimum requirements set by the UKVI to enable sponsorship of migrant workers. Further information can be found at: https://uod.ac.uk/2qUx1RR

For further information about this position please contact Dr Rosie Jackson at rjackson001@dundee.ac.uk .

The closing date for applications 25th of November.

At the University we benefit from having access to a range of personal and professional development courses and training opportunities, we enjoy 34 days annual leave per year and are supported by a range of Work Life Balance policies, staff support networks, membership of Athena SWAN and Stonewall as well as a full range of disability services which all create an enjoyable and inclusive place to work. It is the diversity of our staff and students that make the University of Dundee an enjoyable place to work.

The School of Life Sciences at the University of Dundee is a world-class academic institution with a reputation for the excellence of its research, its high quality teaching and student experience, and the strong impact of its activities outside academia. With 900 staff from over 40 countries worldwide the School provides a dynamic, multi-national, collegiate and diverse environment with state-of-the-art laboratory, technology and teaching facilities.

We are recruiting for exceptional individuals to join us as postdoctoral research assistants within our Biological Chemistry and Drug Discovery Division, to work in the area of trypanosomatid molecular biology. This is a fixed-term appointment for up to 16 months.

We are looking for highly motivated researchers with appropriate skills in molecular and cell biology to work in the area of trypanosomatid molecular biology. The project is funded by Wellcome and a major goal is to understand gene expression control in African trypanosomes (see https://sites.dundee.ac.uk/david-horn/).

Projects may focus on gene expression control by RNA-binding proteins, expression of Variant Surface Glycoprotein related genes, or core histone tail editing.

Candidates interested in parasites that cause neglected tropical diseases and in applying state-of-the-art genetic technologies to these parasites should apply.

Please note that applications made on a part-time basis for this role will/will not be considered.

Your priorities will include:

• To pursue a research project involving predominantly molecular genetic and cell biology techniques.


• Work independently, and contribute to the teaching/training of other staff/Ph.D. students.


• Contribute to the life of the School of Life Sciences

Who we're looking for:

Essential:

• A PhD in a relevant subject


• Significant experience contributing to molecular biology projects in the laboratory


• Publication(s) in peer-reviewed journals


• Ability to work independently and/or as part of a team


• Experience with cell culture Desirable:


• Experience with containment level two pathogens


• Computer and data processing skills


• Good communication skills, both written and verbal

We are one of the UK's leading universities, internationally recognised for our expertise across a range of disciplines and research breakthroughs in multiple areas, including science, medicine and engineering, amongst many others. Our purpose is to transform lives, locally and globally, which we do as a community of staff (Professional Services and academic Schools), students and alumni. Professional Services directorates are key to delivering the University strategy and driving change across the University.

For further information about this position please contact Professor David Horn d.horn@dundee.ac.uk To find out more about Group/Unit/Team/School please visit the Website.

Commitment to DORA

The School of Life Sciences has been fully committed to the principals of the San Francisco Declaration on Research Assessment (DORA) since 2013. In assessing applicants, we consider the scientific quality of their published research papers, but do not take into account where the papers were published and do not consider journal-based metrics, such as Journal Impact Factors.

The diversity of our staff and students helps to make the University of Dundee a UK university of choice for undergraduate, postgraduate and distance learning. Family friendly policies, staff networks for BME, Disabled and LGBT staff, membership of Athena SWAN, the ECU Race Equality Charter and Stonewall as well a full range of disability services, create an enjoyable and inclusive place to work.

Grade UE06: £33,882 to £39,105 per annum, pro rata if part time
Institute of Ecology and Evolution / School of Biological Sciences / College of Sciences and Engineering
Full time: 35 hours per week
Fixed Term: for 24 months (Start date 1st March 2025)

We are looking for a Research Technician in Temporal Genomics and Metagenomics

This post is advertised as full-time (35 hours per week), however, we are open to considering part-time or flexible working patterns.

The Opportunity:

We are seeking an experienced research technician (RT) who will plan and carry out experimental work on museum specimens from various mammals and their associated microbiomes, as well as contribute to the efficient day-to-day running of the ancient DNA lab. The main job purpose is to assist with ongoing research on (meta)genomics of population declines, working with multiple mammalian species from around the world. This will involve extracting DNA from historical samples using ancient DNA techniques in the specialised environment of the ancient DNA lab, constructing next generation sequencing libraries, and performing quality checks. Contribution to sampling in the natural history museums and data analysis is possible. We therefore require a candidate with a graduate or postgraduate degree in a relevant field.

Your skills and attributes for success:

Molecular wet lab experience, in particular with DNA extraction and next generation library preparation
Excellent time management and organisational skills, great attention to detail
Providing training and supervision to both students and other lab members and supporting their experimental work
Experience working with degraded samples or ancient DNA molecular work

We are recruiting for an exceptional individual to join us as a Postdoctoral Researcher within The Stanley-Wall Laboratory, Molecular Microbiology, School of Life Sciences, with experience in bacterial genetics, transcriptions and/or microscopy (https://www.dundee.ac.uk/people/nicola-stanley-wall). This is a fixed-term appointment for up to 42 months.

We investigate mechanisms underpinning Bacillus subtilis biofilm formation and conduct interdisciplinary studies combining classical molecular genetics, microbiology, and soft matter physics.

We aim to uncover key regulatory mechanisms underpinning Bacillus subtilis biofilm matrix remodelling, function, resilience, and competitiveness, that direct the ability of this organism to occupy a wide range of environmental niches. The successful applicants will exploit recent findings to uncover the molecular processes driving adaptation of the biofilm matrix and the impact for the function and success of the bacteria in different environments.

The project builds on our published work (see https://pubmed.ncbi.nlm.nih.gov/36528619/; https://pubmed.ncbi.nlm.nih.gov/34486975/). You will be part of a collaborative research project with colleagues based at the University of Edinburgh (Prof. Cait MacPhee and Dr. Ryan Morris).

The appointment as a Postdoctoral Research Assistant on the Grade 7 salary scale is dependent upon you having been awarded a PhD. An appointment may be considered if you are shortly expected to be awarded a PhD. In this case, the initial appointment would be made as a Research Assistant on the Training Grade 7 salary scale (Spinal Point 25 - 28).

To apply, please submit a single PDF file that contains:

• A cover letter that outlines your research interests and career goals, alongside a summary highlighting your expertise in microbial genetics and gene expression analysis.
• A curriculum vitae containing a list of publications and/or preprints with a brief description of your contribution to each piece of work.

It is intended that interviews for short listed candidates will be held on the 18th and/or 19th of November 2024.

Your priorities will include:

• Transcriptomic analysis of Bacillus subtilis biofilms in different environmental context
• Analysis of B. subtilis survival and adaptation to different contexts
• Engaging members of the public in our research

Who we're looking for:

Successful candidates will have a strong background in bacterial genetics, ideally with expertise in transcriptomics and/or microscopy. You should be creative, enthusiastic to solve challenging problems, be a team player, be equipped with excellent communication skills and have an awareness of working in a positive research culture.

Candidates are expected to have expertise in:

• Molecular biology, bacteriology
• Transcriptomic analysis

And/or

• Flow cytometry
• Microscopy
• Knowledge of biofilm formation Additional desired skills are:
• Undergraduate student supervision in laboratory settings
• Tutoring undergraduates

For further information about this position please contact Prof Nicola Stanley-Wall (Molecular Microbiology/School of Life Sciences) at n.r.stanleywall@dundee.ac.uk. To find out more about the Division of Molecular Microbiology (MMB) please visit https://www.dundee.ac.uk/life-sciences/research/molecular-microbiology

REGIUS CHAIR OF MEDICAL SCIENCE, UNIVERSITY OF EDINBURGH
Grade ACN4: £96,963 to £128,841 per year
College of Medicine and Veterinary Medicine
Full time: 40 hours per week
Open ended: Permanent

Applications are invited for the University’s prestigious Regius Chair of Medical Science, which is vacant following the retirement of Sir John Savill.

The Opportunity:

We are seeking to appoint an outstanding medical scientist to the post. The major remit of the role is to provide outward-facing integrated strategic leadership in medical research and innovation, supporting the University’s 2030 strategic plan and the vision for developing the University’s BioQuarter as the UK’s leading Health Innovation District. This role complements CMVMs expert Deans to bring together a transformative vision across disciplines that will help college grow and shape our research capability to achieve maximal impact and societal benefit.

The postholder will report to the Head of College of Medicine and Veterinary Medicine and support the College Dean of Research. The Regius Chair will be a member of the College Senior Leadership Team and member of the College Research Committee.

We anticipate NHS Lothian will offer an honorary consultant contract for applicants who remain clinically active.

We welcome applications from everyone irrespective of gender or ethnic group. As women and members of ethnic minorities are currently under-represented in posts at this level we particularly encourage applications from members of these groups.

Informal Enquiries can be made, in confidence to Professor David Argyle, Head of College and Vice Principal for Medicine and Veterinary Medicine (David.argyle@ed.ac.uk).

We encourage all applicants to apply online at www.jobs.ed.ac.uk. The application process is quick and easy to follow, and you will receive email confirmation of safe receipt of your application. The online system allows you to submit a CV.

a full academic CV, including your contributions to supporting the wider research system; and
a covering letter (of no more than two A4 pages) outlining your interest in, and vision for, the role.
Your skills and attributes for success:

Clinically Qualified in Medicine but with a good understanding of the pathways from basic science to translational clinical delivery.
Internationally respected personal research record in the area of medical science and translation. Ideally with impactful research spanning from bench to clinic.
Exceptional strategic medical research leadership experience and impact at national level.
Record of engaging successfully with major UK research funders, with government(s), policy makers and industry

We are recruiting for an exceptional individual to join as a Postdoctoral Researcher in the laboratory of Dr Arpan Mehta. This is a fixed-term appointment for 18 months, with potential extension at the end of the term.

We are recruiting for a driven individual to join the laboratory of Dr Arpan Mehta, a clinician-scientist, with expertise in cell biology and/or gene-editing to conduct an innovative pooled CRISPR screen in human motor neurons derived from induced pluripotent stem cells. The overarching goal of the lab is to undertake fundamental research to understand the molecular basis of amyotrophic lateral sclerosis (ALS), a form of motor neuron disease (MND), through open and interdisciplinary collaborations within and outwith of our unit.

The successful applicant will undertake a project as part of the MND Accelerator (MNDAcc) initiative funded by the Medical Research Council and National Institute for Health and Care Research to make the translation of discoveries into therapeutics easier for motor neuron disease and frontotemporal dementia. The goal is to make robust discoveries and share data openly in the space of 18 months.

Your priorities will include:

• Build C9ORF72-iCas9 iPS cell line and perform quality control followed by differentiation to motor neurons and microglia using published protocols.
• Optimise and perform a kinome-wide CRSIPR/Cas9 knock out-screen and sgRNA enrichment analysis.
• Validate the top candidate hits and create a CROP-seq library in partnership with UK Dementia Research Institute (UK DRI) single-cell facility.
• Public and patient involvement and engagement presentations.
• Dissemination of protocols and data openly and through formal peer-reviewed publications.
• Advising and mentoring undergraduate and PhD students.

Candidate requirements:

• PhD in molecular biology with a track record of academic success.

• Highly organised, motivated and meticulous, with an ability to work independently and to drive a project forwards robustly and at pace.
• Expertise in iPS cell culture is highly desirable, although the successful candidate would be supported and trained (if necessary) by Dr Lindsay Davidson who leads our iPSC core facility.
• Prior experience in gene editing and CRISPR screens would be highly desirable.

We are one of the UK's leading universities, internationally recognised for our expertise across a range of disciplines and research breakthroughs in multiple areas, including science, medicine and engineering, amongst many others. Our purpose is to transform lives, locally and globally, which we do as a community of staff (Professional Services and academic Schools), students and alumni. Professional Services directorates are key to delivering the University strategy and driving change across the University.

For further information about this position please contact Dr Arpan Mehta at amehta001@dundee.ac.uk. To find out more about MRC PPU please visit https://www.ppu.mrc.ac.uk/

Grade UE07- £40, 247- £47,874

College of Science & Engineering- School of Engineering

Full Time: 35 hours per week

Fixed Term: 46 months



The Opportunity:

This exciting position is supporting the new Centre for Net Zero High Density Buildings (CeNZ-HighDB) within the Green Materials, Building Performance and Building Archetypes by contributing with the research and development, outreach and industry partner collaboration across a portfolio of projects. A primary aim of the Centre is to accelerate the green economy outcomes and impacts for the built environment and construction sector to deliver net zero.

Supporting the development of projects under the Green Materials, Building Performance and Building Archetypes TWG of the Centre, the role holder will help to deliver funded projects between the university and industry partners, within the remit of the TWG. The post-holder will report to the TWG Academic Lead to develop projects that involve the thermal performance of buildings, including energy efficiency, green thermal materials and products, carbon emission reduction methods and delivery initiatives in the retrofit of existing buildings through the archetype approach. This PDRA post, is contracted by the School of Engineering and based at the Edinburgh Futures Institute (EFI) aligned to the Centre for Future Infrastructure (CFI). The individual will work in close collaboration with other PDRA’s of different TWG’s of the Centre to form a research and management community.

This post is full-time (35 hours per week) over 46 months, however, we are open to considering part-time or flexible working patterns. We are also open to considering requests for hybrid working (on a non-contractual basis) that combines a mix of remote and regular on-campus working.



Your skills and attributes for success:

Experience in Scottish/ UK building methods of construction, including heritage and conservation typologies,
Knowledge in the thermal performance of building components, materials and products,
Appreciation of the research and development of green materials and products, primarily for use in the reduction of heat loss in buildings,
Ability to collaborate in a research and project management capacity with Scottish and/ or UK companies,
Experience in the carbon emissions and energy reduction methods in existing buildings built in Scotland/ UK.

We are recruiting highly motivated postdoctoral researchers to participate in a new academic-industrial global initiative supported by the Michael J Fox Foundation for Parkinson's Research. The project aims to: (1) Explore and validate new approaches to target LRRK2; (2) Perform systematic mechanistic, structural and safety analyses to benchmark new LRRK2 modifiers that emerge from this effort and (3) identify clinically relevant biomarkers for LRRK2-driven Parkinson's disease that will facilitate the selection of patients who respond to LRRK2 inhibitor therapy. We aim to galvanise research and accelerate the development of Parkinson's disease therapeutics. These positions enable further training in state-of-the-art methods through the course of the project, and involve wider collaboration with Protein Phosphorylation and Ubiquitylation Unit members, other academic Institutions worldwide and industrial partners working in this area.

The appointed post holders will be based within the laboratories of Dario Alessi, Esther Sammler and Paul Davies within the University of Dundee's MRC Protein Phosphorylation and Ubiquitylation Unit (MRC-PPU, http://www.ppu.mrc.ac.uk/).

The successful applicant will have previous knowledge and expertise in one or more of the following areas:

1. Mechanistic cell biology employing a multidisciplinary approach including molecular, biochemical, physiological, mass spectrometry, pharmacological and genetic methodologies.


2. Screening and characterisation of compounds in in vitro and in vivo assays.


3. Protein purification.


4. Structural biology.


5. Computational and AI modelling for hit discovery and optimisation.


6. Biophysical assays to investigate protein/protein interactions and for compound screening.


7. Quantitative mass spectrometry analysis (proteomic, lipidomic, metabolomic, post translational modifications), preferably in clinical samples.


8. Bioinformatic methodologies and analysis of large datasets including mass spectrometry data.

Your priorities will include:

• 
  
  
  
  • To lead a research project in the relevant discipline area using the appropriate methods and/or techniques.
  
  
  • To take responsibility for project development and implementation, including experimental design and identification and development of a broad range of techniques necessary to achieve the research objectives.
  
  
  • To collaborate with research colleagues and support staff internally as appropriate to the research.
  
  
  • To provide guidance and support to other staff and students associated with the project.
  
  
  • To support the production of research reports and/or publications as required by the funding body or for dissemination to the wider academic community.
  
  
  • To undertake any other duties relevant to the programme of research as required.
  
  
  
  

Who we're looking for:

• 
  
  
  
  • Applicants must have a PhD in a relevant discipline with strong academic track record and at least one first authored publication either submitted to a preprint server or published in an internationally recognised peer-reviewed journal.
  
  
  • Significant hands-on expertise in one or more of the following: biochemistry, mass spectrometry, cell biology, molecular biology, structural biology, signal transduction, data analysis and bioinformatic analysis.
  
  
  • Strong knowledge and interest in understanding pathways that are linked to neurodegeneration and Parkinson's disease and an appreciation of how research in this area can be exploited to accelerate drug discovery.
  
  
  • Hands-on experience in experimental techniques and data analysis that are relevant to the role.
  
  
  • Experience in independent research projects including interdisciplinary work.
  
  
  • Ability to work in a team in a highly collaborative manner, embracing the principles of Open Science.
  
  
  • Excellent interpersonal and organisational skills.
  
  
  • Excellent knowledge of the English language is essential.
  
  
  • Experience in multi-institutional and/or industry collaborations is highly desirable.